Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.38 |
| ▸ | MET | P08581 | 4/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | MST1R | Q04912 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | HGF | P14210 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25914917 | 0.90 | CYP3A4 (0.35) | KDRMETLCKMST1RAURKA | |
| SCHEMBL25914717 | 0.85 | CSF1R (0.42) | KDRMETLCKMST1RAURKA | |
| SCHEMBL25915040 | 0.84 | KDR (0.37) | KDRMETLCKMST1RAURKA | |
| SCHEMBL25910908 | 0.83 | CSF1R (0.41) | KDRMETLCKMST1RAURKA | |
| SCHEMBL25914759 | 0.83 | LCK (0.44) | KDRMETLCKMST1RAURKA | |
| SCHEMBL25914712 | 0.81 | CYP3A4 (0.45) | CYP3A4MAPTTP53 | |
| SCHEMBL25914529 | 0.80 | GAA (0.41) | KDRLCKCSF1RPDGFRBKIT | |
| SCHEMBL25914570 | 0.78 | CSF1R (0.42) | KDRMETLCKMST1RAURKA | |
| SCHEMBL25910688 | 0.78 | CSF1R (0.40) | KDRMETLCKMST1RAURKA | |
| SCHEMBL25914528 | 0.77 | GAA (0.45) | KDRCYP3A4MAPTMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |