Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | HGF | P14210 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
| ▸ | MST1R | Q04912 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25914718 | 0.90 | KDR (0.38) | CYP3A4KDRLCKAURKARPS6KA5 | |
| SCHEMBL25914916 | 0.84 | CSF1R (0.36) | KDRLCKAURKARPS6KA5MET | |
| SCHEMBL25910916 | 0.82 | CSF1R (0.35) | KDRLCKAURKARPS6KA5MET | |
| SCHEMBL25915040 | 0.79 | KDR (0.37) | CYP3A4KDRLCKAURKARPS6KA5 | |
| SCHEMBL25914759 | 0.79 | LCK (0.44) | KDRLCKAURKARPS6KA5MET | |
| SCHEMBL25914939 | 0.77 | CSF1R (0.36) | KDRLCKAURKARPS6KA5MET | |
| SCHEMBL25914529 | 0.76 | GAA (0.41) | CYP3A4KDRLCKMAPTMEN1 | |
| SCHEMBL25910918 | 0.76 | CSF1R (0.35) | CYP3A4KDRLCKMETMST1R | |
| SCHEMBL25914717 | 0.75 | CSF1R (0.42) | KDRLCKAURKARPS6KA5MET | |
| SCHEMBL25914740 | 0.74 | CSF1R (0.35) | LCKMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |