Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25914415 | 0.87 | PDGFRB (0.35) | EGFRFGFR1PDGFRBCSF1RCYP2C9 | |
| SCHEMBL25319475 | 0.84 | CSF1R (0.47) | EGFRFGFR1PDGFRBCSF1RCYP2C9 | |
| SCHEMBL25317492 | 0.84 | PDGFRB (0.35) | EGFRFGFR1PDGFRBCSF1RCYP2C9 | |
| SCHEMBL25914852 | 0.78 | CSF1R (0.40) | EGFRFGFR1PDGFRBCSF1RCYP2C9 | |
| SCHEMBL25910929 | 0.76 | BRAF (0.40) | PDGFRBCSF1RCYP2C9PDGFRALCK | |
| SCHEMBL25910931 | 0.75 | GCK (0.44) | PDGFRBCSF1RCYP2C9PDGFRALCK | |
| SCHEMBL25910943 | 0.75 | CSF1R (0.38) | EGFRFGFR1PDGFRBCSF1RCYP2C9 | |
| SCHEMBL25910939 | 0.75 | CSF1R (0.38) | PDGFRBCSF1RCYP2C9PDGFRALCK | |
| SCHEMBL25914664 | 0.73 | ESR1 (0.38) | EGFRFGFR1PDGFRBCSF1RCYP2C9 | |
| SCHEMBL25913145 | 0.72 | ESR1 (0.37) | FGFR1PDGFRBCSF1RCYP2C9PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |