Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.35 |
| ▸ | WEE1 | P30291 | 4/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25914415 | 0.87 | PDGFRB (0.35) | PDGFRBCSF1RPDGFRALCKKIT | |
| SCHEMBL25317420 | 0.84 | ESR1 (0.40) | PDGFRBCSF1RPDGFRALCKKIT | |
| SCHEMBL25914850 | 0.84 | EGFR (0.35) | PDGFRBCSF1RPDGFRALCKKIT | |
| SCHEMBL25319475 | 0.84 | CSF1R (0.47) | PDGFRBCSF1RPDGFRALCKKIT | |
| SCHEMBL25914414 | 0.72 | CSF1R (0.37) | PDGFRBCSF1RPDGFRALCKKIT | |
| SCHEMBL25317161 | 0.71 | ESR1 (0.43) | PDGFRBCSF1RPDGFRALCKKIT | |
| SCHEMBL31010902 | 0.71 | ESR1 (0.43) | PDGFRBCSF1RPDGFRALCKKIT | |
| SCHEMBL25910804 | 0.70 | BRAF (0.44) | PDGFRBCSF1RPDGFRALCKKIT | |
| SCHEMBL25915038 | 0.70 | GABRA1 (0.30) | — | |
| SCHEMBL25911603 | 0.70 | CSF1R (0.48) | PDGFRBCSF1RPDGFRALCKKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |