Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10523486 | 0.84 | SMN1; SMN2 (0.48) | NOS1SMN1; SMN2RAB9ANPC1GABRA5 | |
| SCHEMBL3615864 | 0.80 | GABRA5 (0.48) | NOS1SMN1; SMN2RAB9ANOS3NOS2 | |
| SCHEMBL13044712 | 0.78 | SLC6A3 (0.45) | NOS1SMN1; SMN2RAB9ANOS3NOS2 | |
| SCHEMBL5911714 | 0.78 | — | — | |
| SCHEMBL19091148 | 0.78 | SMN1; SMN2 (0.52) | NOS1SMN1; SMN2RAB9ANPC1GABRA5 | |
| SCHEMBL4970134 | 0.77 | SMN1; SMN2 (0.59) | NOS1SMN1; SMN2RAB9ANPC1GABRA5 | |
| SCHEMBL13045053 | 0.77 | SLC6A3 (0.44) | NOS1NOS3NOS2ALDH1A1MEN1 | |
| SCHEMBL28682965 | 0.76 | RAB9A (0.53) | NOS1SMN1; SMN2RAB9ANPC1GABRA5 | |
| SCHEMBL13045050 | 0.76 | SLC6A3 (0.43) | NOS1NOS3NOS2 | |
| SCHEMBL307817 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141262-A1 | BAX ACTIVATORS AND USE THEREOF | IPSEN PHARMA S.A.S. (FR) | 2023-07-27 | — | — | WO | disclosed |