SCHEMBL25916333

SCHEMBL25916333

COc1ccc(-c2nc3ccccc3s2)c(NC(=O)c2ccccc2)c1

nearest known ligand 0.75

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.75
TP53 P04637 6/20 0.75
RXFP1 Q9HBX9 1/20 0.71
LMNA P02545 2/20 0.66
SMN1; SMN2 Q16637 2/20 0.65
SCD O00767 3/20 0.60
MEN1 O00255 5/20 0.60
KMT2A Q03164 5/20 0.60
NPC1 O15118 3/20 0.60
RAB9A P51151 3/20 0.60
DHODH Q02127 1/20 0.59
HPGD P15428 2/20 0.59
KDM4E B2RXH2 1/20 0.59
ALDH1A1 P00352 1/20 0.59
MMP2 P08253 1/20 0.55
MMP9 P14780 1/20 0.55
MMP8 P22894 1/20 0.55
MMP13 P45452 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30362804 1.00 MAPT (0.75) MAPTTP53RXFP1LMNASMN1; SMN2
SCHEMBL25916313 0.92 MAPT (0.77) MAPTTP53RXFP1LMNASMN1; SMN2
SCHEMBL30362766 0.92 MAPT (0.77) MAPTTP53RXFP1LMNASMN1; SMN2
SCHEMBL25916335 0.90 MAPT (0.64) MAPTTP53RXFP1LMNASMN1; SMN2
SCHEMBL30362797 0.90 MAPT (0.64) MAPTTP53RXFP1LMNASMN1; SMN2
SCHEMBL25916518 0.85 MAPT (0.70) MAPTTP53RXFP1LMNASMN1; SMN2
SCHEMBL25916842 0.85 MAPT (0.66) MAPTTP53RXFP1SMN1; SMN2SCD
SCHEMBL30362646 0.83 HPGD (0.78) MAPTTP53RXFP1LMNASMN1; SMN2
SCHEMBL25916294 0.83 HPGD (0.78) MAPTTP53RXFP1LMNASMN1; SMN2
SCHEMBL12963290 0.83 MAPT (1.00) MAPTTP53RXFP1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115768631-A Fluorescent composition comprising at least one benzoxazole compound for protecting products 犯罪科学技术公司 2023-03-07 CN claimed
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-07-27 US disclosed
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS TUBB3, TUBA3C, PHB1 MAPT 318/4885TP53 905/4885RXFP1 1340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.