SCHEMBL25916335

SCHEMBL25916335

COc1ccc(-c2nc3ccccc3s2)c(NC(=O)c2ccc(C(F)(F)F)cc2)c1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 14/20 0.64
TP53 P04637 7/20 0.64
RXFP1 Q9HBX9 4/20 0.64
SMN1; SMN2 Q16637 2/20 0.61
LMNA P02545 2/20 0.60
KMT2A Q03164 4/20 0.56
MEN1 O00255 3/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
SCD O00767 1/20 0.56
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
GAA P10253 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
THRB P10828 1/20 0.52
DHODH Q02127 1/20 0.51
MGAM O43451 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30362797 1.00 MAPT (0.64) MAPTTP53RXFP1SMN1; SMN2LMNA
SCHEMBL25916314 0.93 MAPT (0.66) MAPTTP53RXFP1SMN1; SMN2LMNA
SCHEMBL25916333 0.90 MAPT (0.75) MAPTTP53RXFP1SMN1; SMN2LMNA
SCHEMBL30362804 0.90 MAPT (0.75) MAPTTP53RXFP1SMN1; SMN2LMNA
SCHEMBL25916384 0.87 MAPT (0.57) MAPTTP53RXFP1SMN1; SMN2LMNA
SCHEMBL30362775 0.85 HPGD (0.65) MAPTTP53RXFP1LMNATHRB
SCHEMBL25916297 0.85 HPGD (0.65) MAPTTP53RXFP1LMNATHRB
SCHEMBL30362639 0.85 MAPT (0.55) MAPTTP53RXFP1SMN1; SMN2KMT2A
SCHEMBL25916341 0.85 MAPT (0.55) MAPTTP53RXFP1SMN1; SMN2KMT2A
SCHEMBL30362766 0.83 MAPT (0.77) MAPTTP53RXFP1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115768631-A Fluorescent composition comprising at least one benzoxazole compound for protecting products 犯罪科学技术公司 2023-03-07 CN claimed
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS TUBB3, TUBA3C, PHB1 MAPT 318/4885TP53 905/4885RXFP1 1340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.