SCHEMBL25916347

SCHEMBL25916347

O=C(Nc1cccc(Cl)c1-c1nc2ccccc2s1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.60
MMP2 P08253 1/20 0.58
MMP9 P14780 1/20 0.58
MMP8 P22894 1/20 0.58
MMP13 P45452 1/20 0.58
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
NPC1 O15118 3/20 0.55
RAB9A P51151 3/20 0.55
HPGD P15428 4/20 0.55
TP53 P04637 4/20 0.54
LMNA P02545 1/20 0.54
SCD O00767 2/20 0.51
RXFP1 Q9HBX9 1/20 0.51
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30362562 1.00 MAPT (0.60) MAPTMMP2MMP9MMP8MMP13
SCHEMBL25916348 0.89 MAPT (0.52) MAPTMMP2MMP9MMP8MMP13
SCHEMBL30362723 0.89 MAPT (0.52) MAPTMMP2MMP9MMP8MMP13
SCHEMBL25916294 0.81 HPGD (0.78) MAPTMMP2MMP9MMP8MMP13
SCHEMBL30362646 0.81 HPGD (0.78) MAPTMMP2MMP9MMP8MMP13
SCHEMBL29126286 0.81 FSCN1 (0.60) MAPTMMP2MMP9MEN1KMT2A
SCHEMBL25916352 0.81 FSCN1 (0.60) MAPTMMP2MMP9MEN1KMT2A
SCHEMBL29126283 0.81 FSCN1 (0.60) MAPTMMP2MMP9MEN1KMT2A
SCHEMBL30362693 0.79 MAPT (0.61) MAPTMMP2MMP9MMP8MMP13
SCHEMBL25916362 0.79 MAPT (0.61) MAPTMMP2MMP9MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115768631-A Fluorescent composition comprising at least one benzoxazole compound for protecting products 犯罪科学技术公司 2023-03-07 CN claimed
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS TUBB3, TUBA3C, PHB1 MAPT 318/4885MMP2 2340/4885MMP9 1418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.