SCHEMBL25916348

SCHEMBL25916348

O=C(Nc1cccc(Cl)c1-c1nc2ccccc2s1)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.52
TP53 P04637 5/20 0.47
LMNA P02545 2/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
HPGD P15428 3/20 0.47
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47
MMP8 P22894 1/20 0.47
MMP13 P45452 1/20 0.47
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.46
MEN1 O00255 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
KMT2A Q03164 1/20 0.46
PTGS1 P23219 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
NPC1 O15118 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30362723 1.00 MAPT (0.52) MAPTTP53LMNASMN1; SMN2HPGD
SCHEMBL30362562 0.89 MAPT (0.60) MAPTTP53LMNASMN1; SMN2HPGD
SCHEMBL25916347 0.89 MAPT (0.60) MAPTTP53LMNASMN1; SMN2HPGD
SCHEMBL25916297 0.84 HPGD (0.65) MAPTTP53LMNAHPGDMMP2
SCHEMBL30362775 0.84 HPGD (0.65) MAPTTP53LMNAHPGDMMP2
SCHEMBL25916341 0.81 MAPT (0.55) MAPTTP53SMN1; SMN2HPGDALDH1A1
SCHEMBL30362639 0.81 MAPT (0.55) MAPTTP53SMN1; SMN2HPGDALDH1A1
SCHEMBL25916384 0.79 MAPT (0.57) MAPTTP53LMNASMN1; SMN2HPGD
SCHEMBL30211749 0.78 MAPT (0.55) MAPTTP53LMNASMN1; SMN2HPGD
SCHEMBL25916307 0.78 MAPT (0.55) MAPTTP53LMNASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115768631-A Fluorescent composition comprising at least one benzoxazole compound for protecting products 犯罪科学技术公司 2023-03-07 CN claimed
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS TUBB3, TUBA3C, PHB1 MAPT 318/4885TP53 905/4885LMNA 105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.