Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11123440 | 0.86 | CTRB1 (0.54) | CTRB1SYKCASP1CTSLCTSB | |
| SCHEMBL11050540 | 0.86 | CTRB1 (0.54) | CTRB1SYKCASP1CTSLCTSB | |
| SCHEMBL7986494 | 0.86 | CTRB1 (0.54) | CTRB1SYKCASP1CTSLCTSB | |
| SCHEMBL29957249 | 0.86 | SYK (0.60) | CTRB1SYKCTSLCTSBCTSS | |
| SCHEMBL18956286 | 0.86 | CTRB1 (0.57) | CTRB1SYKCASP1ATM | |
| SCHEMBL25260283 | 0.86 | CTRB1 (0.57) | CTRB1SYKCASP1ATM | |
| SCHEMBL29955027 | 0.86 | SYK (0.60) | CTRB1SYKCTSLCTSBCTSS | |
| SCHEMBL18939642 | 0.86 | SYK (0.58) | CTRB1SYKCASP1CTSLCTSB | |
| SCHEMBL18939640 | 0.86 | SYK (0.58) | CTRB1SYKCASP1CTSLCTSB | |
| SCHEMBL30141469 | 0.84 | CTRB1 (0.52) | CTRB1SYKCASP1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49594-E1 | Apelin receptor (APJ) agonists and uses thereof | RESEARCH TRIANGLE INSTITUTE (US) | 2023-08-01 | — | — | US | disclosed |