Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KYNU | Q16719 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29659451 | 0.92 | CTRB1 (0.49) | CTRB1SYKCASP1ATMSIRT2 | |
| SCHEMBL78270 | 0.91 | CTRB1 (0.56) | CTRB1SYKCASP1CTSLCTSS | |
| SCHEMBL11123440 | 0.87 | CTRB1 (0.54) | CTRB1SYKCASP1CTSLCTSB | |
| SCHEMBL11050540 | 0.87 | CTRB1 (0.54) | CTRB1SYKCASP1CTSLCTSB | |
| SCHEMBL7986494 | 0.87 | CTRB1 (0.54) | CTRB1SYKCASP1CTSLCTSB | |
| SCHEMBL24461288 | 0.87 | CTRB1 (0.57) | CTRB1SYKCASP1ATMTRPM8 | |
| SCHEMBL29012282 | 0.87 | CTRB1 (0.57) | CTRB1SYKCASP1ATMTRPM8 | |
| SCHEMBL3848649 | 0.87 | ALDH1A1 (0.47) | CTRB1CASP1ATMALDH1A1NPC1 | |
| SCHEMBL7257986 | 0.87 | SYK (0.56) | CTRB1SYKCASP1CTSLCTSB | |
| SCHEMBL7257989 | 0.87 | SYK (0.56) | CTRB1SYKCASP1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268065-A1 | COMPOUNDS AS ERK INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2022-12-29 | — | — | WO | disclosed |