Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.60 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.57 |
| ▸ | CTSK | P43235 | 5/20 | 0.50 |
| ▸ | CTSL | P07711 | 4/20 | 0.50 |
| ▸ | CTSS | P25774 | 4/20 | 0.50 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957249 | 1.00 | SYK (0.60) | SYKCTRB1CTSKCTSLCTSS | |
| SCHEMBL12220545 | 0.88 | SYK (0.69) | SYKCTRB1CTSKCTSLCTSS | |
| SCHEMBL14318309 | 0.88 | SYK (0.59) | SYKCTRB1CTSKCTSLCTSS | |
| SCHEMBL8697513 | 0.87 | CTRB1 (0.70) | SYKCTRB1CTSKCTSLCTSS | |
| SCHEMBL7403909 | 0.87 | CTRB1 (0.70) | SYKCTRB1CTSKCTSLCTSS | |
| SCHEMBL25260283 | 0.86 | CTRB1 (0.57) | SYKCTRB1ATM | |
| SCHEMBL18956286 | 0.86 | CTRB1 (0.57) | SYKCTRB1ATM | |
| SCHEMBL25916366 | 0.86 | CTRB1 (0.51) | SYKCTRB1CTSKCTSLCTSS | |
| SCHEMBL213314 | 0.84 | SYK (0.64) | SYKCTRB1CTSKCTSLCTSS | |
| SCHEMBL8900969 | 0.84 | CTRB1 (0.74) | SYKCTRB1CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |