SCHEMBL25916384

SCHEMBL25916384

Cc1ccc(-c2nc3ccccc3s2)c(NC(=O)c2ccc(C(F)(F)F)cc2)c1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 15/20 0.57
TP53 P04637 4/20 0.57
RXFP1 Q9HBX9 4/20 0.55
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C9 P11712 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
HPGD P15428 2/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
ALDH1A1 P00352 3/20 0.51
LMNA P02545 2/20 0.51
POLB P06746 1/20 0.48
KDM4E B2RXH2 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25916307 0.93 MAPT (0.55) MAPTTP53RXFP1MEN1KMT2A
SCHEMBL30211749 0.93 MAPT (0.55) MAPTTP53RXFP1MEN1KMT2A
SCHEMBL25916842 0.89 MAPT (0.66) MAPTTP53RXFP1MEN1KMT2A
SCHEMBL25916297 0.88 HPGD (0.65) MAPTTP53RXFP1HPGDALDH1A1
SCHEMBL30362775 0.88 HPGD (0.65) MAPTTP53RXFP1HPGDALDH1A1
SCHEMBL30362639 0.88 MAPT (0.55) MAPTTP53RXFP1MEN1KMT2A
SCHEMBL25916341 0.88 MAPT (0.55) MAPTTP53RXFP1MEN1KMT2A
SCHEMBL30362797 0.87 MAPT (0.64) MAPTTP53RXFP1MEN1KMT2A
SCHEMBL25916335 0.87 MAPT (0.64) MAPTTP53RXFP1MEN1KMT2A
SCHEMBL25916758 0.84 MAPT (0.56) MAPTTP53RXFP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS TUBB3, TUBA3C, PHB1 MAPT 318/4885TP53 905/4885RXFP1 1340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.