SCHEMBL25916593

SCHEMBL25916593

COc1ccc(-c2nc3ccccc3s2)c(N(C)C(=O)/C=C/c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
MAPT P10636 8/20 0.47
TP53 P04637 3/20 0.47
RXFP1 Q9HBX9 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.44
RAB9A P51151 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
KDM4E B2RXH2 4/20 0.44
NPC1 O15118 1/20 0.44
PKM P14618 1/20 0.44
MGAM O43451 2/20 0.44
GLO1 Q04760 1/20 0.43
MEN1 O00255 2/20 0.43
ALDH1A1 P00352 2/20 0.43
KMT2A Q03164 2/20 0.43
HPGD P15428 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25916711 0.92 LMNA (0.50) LMNAMAPTTP53RXFP1SMN1; SMN2
SCHEMBL25916602 0.85 FSCN1 (0.42) LMNAMAPTRXFP1SMN1; SMN2RAB9A
SCHEMBL25916689 0.81 FSCN1 (0.44) LMNAMAPTTP53RXFP1SMN1; SMN2
SCHEMBL30362725 0.80 FSCN1 (0.56) LMNAMAPTTP53RXFP1SMN1; SMN2
SCHEMBL29126276 0.80 FSCN1 (0.56) LMNAMAPTTP53RXFP1SMN1; SMN2
SCHEMBL29126275 0.80 FSCN1 (0.56) LMNAMAPTTP53RXFP1SMN1; SMN2
SCHEMBL25916338 0.80 FSCN1 (0.56) LMNAMAPTTP53RXFP1SMN1; SMN2
SCHEMBL30362551 0.78 MAPT (0.57) LMNAMAPTTP53RXFP1SMN1; SMN2
SCHEMBL29126291 0.78 MAPT (0.57) LMNAMAPTTP53RXFP1SMN1; SMN2
SCHEMBL29126289 0.78 MAPT (0.57) LMNAMAPTTP53RXFP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS TUBB3, TUBA3C, PHB1 LMNA 105/4885MAPT 318/4885TP53 905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.