Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 8/20 | 0.55 |
| ▸ | HRH1 | P35367 | 2/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24410134 | 0.82 | HRH2 (0.57) | HRH2HRH1HRH4CYP1A2NOS1 | |
| SCHEMBL5911654 | 0.80 | HRH2 (0.55) | HRH2HRH1HRH4CYP1A2NOS1 | |
| SCHEMBL13459260 | 0.77 | — | — | |
| SCHEMBL1911605 | 0.74 | — | — | |
| SCHEMBL259638 | 0.73 | HRH2 (0.68) | HRH2HRH1HRH4CYP1A2NOS1 | |
| SCHEMBL13458766 | 0.72 | — | — | |
| SCHEMBL25916625 | 0.72 | NOS1 (0.45) | HRH2HRH1HRH4CYP1A2NOS1 | |
| SCHEMBL31661267 | 0.71 | ALDH1A1 (0.60) | CYP1A2FBP1ALDH1A1HSD17B10HPGD | |
| SCHEMBL5911593 | 0.71 | HRH2 (0.70) | HRH2HRH1HRH4CYP1A2NOS1 | |
| Amthamine SCHEMBL400272 | 0.71 | HRH2 (1.00) | HRH2HRH1HRH4CYP1A2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141262-A1 | BAX ACTIVATORS AND USE THEREOF | IPSEN PHARMA S.A.S. (FR) | 2023-07-27 | — | — | WO | disclosed |