Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | MPL | P40238 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25916483 | 0.82 | NOS1 (0.46) | NOS1MPLSMN1; SMN2HSD17B10MAPT | |
| SCHEMBL27910497 | 0.76 | ALDH1A1 (0.33) | HSD17B10HPGDALDH1A1FBP1 | |
| SCHEMBL5911688 | 0.74 | — | — | |
| SCHEMBL25328666 | 0.72 | — | — | |
| SCHEMBL28860933 | 0.72 | — | — | |
| SCHEMBL25916624 | 0.72 | HRH2 (0.55) | NOS1SMN1; SMN2HSD17B10GAAHPGD | |
| SCHEMBL6815280 | 0.69 | NOS1 (0.46) | NOS1SMN1; SMN2HSD17B10MAPTGAA | |
| SCHEMBL965933 | 0.68 | NOS1 (0.50) | NOS1MPLSMN1; SMN2HSD17B10MAPT | |
| SCHEMBL11999656 | 0.68 | NOS1 (0.45) | NOS1SMN1; SMN2HSD17B10MAPTGAA | |
| SCHEMBL1417449 | 0.67 | NOS1 (0.43) | NOS1SMN1; SMN2HSD17B10MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141262-A1 | BAX ACTIVATORS AND USE THEREOF | IPSEN PHARMA S.A.S. (FR) | 2023-07-27 | — | — | WO | disclosed |