Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726929 | 0.98 | PDK1 (0.32) | PDK1PDK2PDK3PDK4SIGMAR1 | |
| SCHEMBL2588015 | 0.95 | PDK1 (0.31) | PDK1PDK2PDK3PDK4SIGMAR1 | |
| SCHEMBL1728200 | 0.84 | GRIA1 (0.37) | — | |
| SCHEMBL1728208 | 0.84 | GRIA1 (0.37) | — | |
| SCHEMBL1728087 | 0.82 | GRIA1 (0.40) | — | |
| SCHEMBL10697148 | 0.79 | ALDH1A1 (0.32) | — | |
| SCHEMBL27822246 | 0.76 | CA5A (0.33) | — | |
| SCHEMBL11954378 | 0.75 | POLB (0.36) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL23613033 | 0.73 | EPHX1 (0.33) | — | |
| SCHEMBL15925065 | 0.73 | MEN1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103416714-A | Sweetness enhancers, sweetness enhanced sweetener compositions, methods for their formulation, and uses | COCA COLA CO | 2013-12-04 | — | — | CN | disclosed |
| CN-101742925-B | Sweetness enhancers, sweetness enhanced sweetener compositions, methods of their formulation, and uses | COCA COLA CO | 2013-08-07 | — | — | CN | disclosed |
| US-20130123135-A1 | Methods To Identify Modulators of TAS2R48 Receptors | GIVAUDAN SA (CH) | 2013-05-16 | — | — | US | disclosed |
| US-20130115624-A1 | Methods To Identify Modulators | GIVAUDAN S.A. (CH) | 2013-05-09 | — | — | US | disclosed |
| EP-2567231-A1 | METHODS TO IDENTIFY MODULATORS OF TAS2R4S RECEPTORS | Givaudan SA (CH) | 2013-03-13 | — | — | EP | disclosed |
| EP-2567229-A1 | METHODS TO IDENTIFY MODULATORS | Givaudan SA (CH) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138456-A1 | METHODS TO IDENTIFY MODULATORS OF TAS2R4S RECEPTORS | GIVAUDAN SA (CH) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011138455-A1 | METHODS TO IDENTIFY MODULATORS | GIVAUDAN SA (CH) | 2011-11-10 | — | — | WO | disclosed |
| CN-101742925-A | Sweetness enhancers, sweetness enhanced sweetener compositions, methods of their formulation, and uses | COCA COLA CO | 2010-06-16 | — | — | CN | disclosed |