⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20320571 | 0.75 | — | — | |
| SCHEMBL1955405 | 0.75 | — | — | |
| SCHEMBL13074067 | 0.73 | KMT2A (0.32) | — | |
| SCHEMBL4603878 | 0.73 | INMT (0.38) | — | |
| SCHEMBL3922485 | 0.71 | ALDH1A1 (0.41) | — | |
| SCHEMBL9394412 | 0.70 | PIK3CD (0.33) | — | |
| SCHEMBL9440237 | 0.69 | MEN1 (0.48) | — | |
| SCHEMBL29881687 | 0.69 | TSHR (0.31) | — | |
| SCHEMBL9440179 | 0.67 | MEN1 (0.47) | — | |
| SCHEMBL4143578 | 0.66 | MEN1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234953-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-27 | — | — | US | disclosed |