Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14413594 | 0.85 | KMT2A (0.50) | MAPTKMT2AL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL15808669 | 0.84 | L3MBTL1 (0.69) | KMT2AL3MBTL1POLBRAB9AMEN1 | |
| SCHEMBL7762330 | 0.84 | L3MBTL1 (0.53) | MAPTKMT2AL3MBTL1POLBALDH1A1 | |
| SCHEMBL7388691 | 0.82 | MAPT (0.48) | MAPTKMT2AL3MBTL1POLBALDH1A1 | |
| SCHEMBL19917089 | 0.81 | KMT2A (0.50) | MAPTKMT2AL3MBTL1POLBALDH1A1 | |
| SCHEMBL28070422 | 0.81 | KMT2A (0.53) | MAPTKMT2AL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL1198628 | 0.79 | NPC1 (0.52) | MAPTKMT2AL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL15826612 | 0.79 | L3MBTL1 (0.57) | MAPTKMT2AL3MBTL1POLBALDH1A1 | |
| SCHEMBL12606498 | 0.79 | KMT2A (0.51) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3966250 | 0.79 | L3MBTL1 (0.47) | MAPTKMT2AL3MBTL1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |