SCHEMBL25919474

SCHEMBL25919474

CC1(C)OB(c2ccc(/C(N)=N/O)cn2)OC1(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F11 P03951 3/20 0.38
GAA P10253 3/20 0.36
RAB9A P51151 3/20 0.36
NPC1 O15118 2/20 0.36
F2 P00734 2/20 0.34
PRSS1 P07477 2/20 0.34
PRSS2 P07478 2/20 0.34
PRSS3 P35030 2/20 0.34
LMNA P02545 2/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CA1 P00915 5/20 0.32
CA2 P00918 5/20 0.32
CA9 Q16790 5/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
KDM4E B2RXH2 1/20 0.32
RECQL P46063 1/20 0.32
LPL P06858 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25919482 0.79 F11 (0.37) F11F2PRSS1PRSS2PRSS3
SCHEMBL25318064 0.78 F11 (0.55) F11F2PRSS1PRSS2PRSS3
SCHEMBL25318058 0.78 F11 (0.55) F11F2PRSS1PRSS2PRSS3
SCHEMBL12993386 0.77 HCAR3 (0.47) MAPTHSD17B10
SCHEMBL25380328 0.73 KMT2A (0.41) ALOX15HSD17B10CA1CA2CA9
SCHEMBL28937267 0.73 MAPK1 (0.51) RAB9ANPC1MAPTCA1CA2
SCHEMBL25378938 0.73 BAZ2B (0.46) CA1CA2CA9CXCR2
SCHEMBL9940656 0.73 LPL (0.34) F11CA1CA2CA9LPL
SCHEMBL9940819 0.73 LPL (0.34) F11LPLLIPG
SCHEMBL2262065 0.71 CCR1 (0.40) RAB9AMAPTLPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023141114-A2 SYNTHESIS OF BORON-CONTAINING AMIDOXIME REAGENTS AND THEIR APPLICATION TO SYNTHESIZE FUNCTIONALIZED OXADIAZOLE AND QUINAZOLINONE DERIVATIVES LONG ISLAND UNIVERSITY (US) 2023-07-27 WO disclosed