SCHEMBL25919609

SCHEMBL25919609

Cc1ccc(/C(N)=N/O)[nH]1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HMBS P08397 1/20 0.42
LMNA P02545 1/20 0.33
GFER P55789 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GAA P10253 2/20 0.31
RAB9A P51151 1/20 0.31
RECQL P46063 1/20 0.31
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17988324 0.76 HMBS (0.43) HMBSKMT2ARAB9A
SCHEMBL14598235 0.73
SCHEMBL6874463 0.72 SPR (0.46) HMBSLMNAL3MBTL1GAA
SCHEMBL872450 0.72 SPR (0.46) HMBSLMNAL3MBTL1GAA
SCHEMBL25919605 0.71 KDM1A (0.35) KDM1A
SCHEMBL25919607 0.66 F11 (0.40)
SCHEMBL1969643 0.64 HMBS (0.41) HMBSLMNAGFERKMT2AL3MBTL1
SCHEMBL65952 0.63
SCHEMBL21363085 0.62 HMBS (0.43) HMBSLMNAKMT2AGAARAB9A
SCHEMBL1972667 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023141114-A2 SYNTHESIS OF BORON-CONTAINING AMIDOXIME REAGENTS AND THEIR APPLICATION TO SYNTHESIZE FUNCTIONALIZED OXADIAZOLE AND QUINAZOLINONE DERIVATIVES LONG ISLAND UNIVERSITY (US) 2023-07-27 WO disclosed