Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 13/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25321489 | 1.00 | RIPK1 (0.43) | RIPK1PRMT5WDR77TACR1ALDH1A1 | |
| SCHEMBL25321486 | 1.00 | RIPK1 (0.43) | RIPK1PRMT5WDR77TACR1ALDH1A1 | |
| SCHEMBL25321972 | 0.80 | FABP7 (0.41) | RIPK1PRMT5WDR77TACR1 | |
| SCHEMBL25920109 | 0.80 | FABP7 (0.41) | RIPK1PRMT5WDR77TACR1 | |
| SCHEMBL25321968 | 0.80 | FABP7 (0.41) | RIPK1PRMT5WDR77TACR1 | |
| SCHEMBL25324578 | 0.79 | PRMT5 (0.58) | RIPK1PRMT5WDR77ALDH1A1CHRNB2 | |
| SCHEMBL25324576 | 0.79 | PRMT5 (0.58) | RIPK1PRMT5WDR77ALDH1A1CHRNB2 | |
| Ammonia Solution, Strong SCHEMBL25323728 | 0.78 | PRMT5 (0.57) | RIPK1PRMT5WDR77ALDH1A1CHRNB2 | |
| Ammonia Solution, Strong SCHEMBL25323733 | 0.78 | PRMT5 (0.57) | RIPK1PRMT5WDR77ALDH1A1CHRNB2 | |
| SCHEMBL25323285 | 0.75 | CHRNB2 (0.44) | RIPK1ALDH1A1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |