SCHEMBL25920150

SCHEMBL25920150

CCc1ccc2c(c1)c1cc(CC)ccc1n2-c1ccccc1-c1ccc2c(c1)c1ccccc1n2-c1ccccc1-c1ccc2c(c1)c1ccccc1n2-c1ccc(-c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 3/20 0.40
KDM4E B2RXH2 2/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PGR P06401 1/20 0.37
RORA P35398 1/20 0.37
RORC P51449 1/20 0.37
RORB Q92753 1/20 0.37
AKR1C4 P17516 1/20 0.37
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37
PTGES O14684 1/20 0.36
RAC2 P15153 1/20 0.36
RAC3 P60763 1/20 0.36
CDC42 P60953 1/20 0.36
RAC1 P63000 1/20 0.36
PTGER4 P35408 1/20 0.36
NPY5R Q15761 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25920232 0.93 TSPO (0.39) TSPOKDM4EATML3MBTL1PGR
SCHEMBL28339424 0.90 PGR (0.41) TSPOKDM4EATML3MBTL1PGR
SCHEMBL13542510 0.90 KDM4E (0.49) TSPOKDM4EATML3MBTL1PGR
SCHEMBL25919261 0.89 L3MBTL1 (0.50) TSPOKDM4EATML3MBTL1AKR1C4
SCHEMBL25918822 0.89 L3MBTL1 (0.50) TSPOKDM4EATML3MBTL1AKR1C4
SCHEMBL25919267 0.87 L3MBTL1 (0.49) TSPOKDM4EATML3MBTL1AKR1C4
SCHEMBL25925301 0.87 L3MBTL1 (0.49) TSPOKDM4EATML3MBTL1AKR1C4
SCHEMBL25936867 0.87 L3MBTL1 (0.49) TSPOKDM4EATML3MBTL1AKR1C4
SCHEMBL16268823 0.87 KDM4E (0.47) TSPOKDM4EATML3MBTL1PGR
SCHEMBL262989 0.85 TSPO (0.44) TSPOKDM4EATML3MBTL1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023142485-A1 BORON-NITROGEN COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 季华恒烨(佛山)电子材料有限公司 2023-08-03 WO disclosed