Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18616784 | 0.80 | MAOA (0.51) | GAAKDM4EMAPTHTTDRD2 | |
| SCHEMBL25316370 | 0.78 | CA1 (0.54) | ADRB2ADRB1ADRB3OPRM1OPRK1 | |
| SCHEMBL13507845 | 0.75 | GAA (0.47) | ADRB2GAAKDM4EMAPTHTT | |
| SCHEMBL20883964 | 0.75 | KDM1A (0.47) | ADRB2GAAKDM4EMAPTHTT | |
| SCHEMBL25920425 | 0.74 | OPRM1 (0.41) | ADRB2GAAKDM4EMAPTHTT | |
| SCHEMBL17776133 | 0.74 | PRCP (0.65) | ADRB2ADRB1ADRB3GAAKDM4E | |
| SCHEMBL31482774 | 0.74 | PRCP (0.65) | ADRB2ADRB1ADRB3GAAKDM4E | |
| SCHEMBL7364212 | 0.74 | PRCP (0.65) | ADRB2ADRB1ADRB3GAAKDM4E | |
| Hydrochloric Acid SCHEMBL31397779 | 0.72 | PRCP (0.63) | ADRB2ADRB1ADRB3GAAKDM4E | |
| Hydrochloric Acid SCHEMBL31482772 | 0.72 | PRCP (0.63) | ADRB2ADRB1ADRB3GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |