SCHEMBL2592084

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2591434	0.85	TDP1 (0.42)	KDM4EALDH1A1TP53NR3C1KMT2A
	SCHEMBL12498592	0.79	KDM4E (0.42)	KDM4EPPARAHTTHSD17B10ALDH1A1
	SCHEMBL26259137	0.75	PPARA (0.48)	KDM4EPPARAHSD17B10ALDH1A1TP53
	SCHEMBL2588507	0.75	MTOR (0.38)	KDM4EKMT2A
	SCHEMBL2594202	0.74	KDM4E (0.41)	KDM4EHTTAKR1C3AKR1C2HSD17B10
	SCHEMBL1694840	0.73	NR3C1 (0.41)	KDM4EPPARAHSD17B10ALDH1A1NR3C1
	SCHEMBL2588942	0.72	KDM4E (0.53)	KDM4EMYCNR4A1AKR1C4AKR1C3
	SCHEMBL2594981	0.72	MYC (0.37)	KDM4EPPARAHTTMYCNR4A1
	SCHEMBL31474839	0.72	KDM4E (0.53)	KDM4EMYCNR4A1AKR1C4AKR1C3
	SCHEMBL12180762	0.72	KDM4E (0.33)	KDM4EPPARAHSD17B10ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.