⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25933529 | 0.84 | — | — | |
| SCHEMBL25921614 | 0.84 | — | — | |
| SCHEMBL23219733 | 0.80 | FDPS (0.33) | — | |
| SCHEMBL26770404 | 0.79 | RORC (0.30) | — | |
| SCHEMBL24453312 | 0.74 | OPRM1 (0.30) | — | |
| SCHEMBL25922397 | 0.72 | FDPS (0.31) | — | |
| SCHEMBL26782756 | 0.72 | — | — | |
| SCHEMBL25812965 | 0.72 | FDPS (0.31) | — | |
| SCHEMBL22000500 | 0.71 | FDPS (0.32) | — | |
| SCHEMBL25813089 | 0.71 | OPRM1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023142754-A1 | EZH1/2 INHIBITOR, PREPARATION THEREOF, AND USE THEREOF IN ANTI-TUMOR THERAPY | 江苏天士力帝益药业有限公司 | 2023-08-03 | — | — | WO | disclosed |