SCHEMBL25922128

SCHEMBL25922128

COc1ccc(S(=O)(=O)c2ccc(Oc3ccc(-c4ccc(O)cc4)cc3)cc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.80
GAA P10253 1/20 0.80
LTA4H P09960 1/20 0.63
ESR2 Q92731 1/20 0.63
ELANE P08246 1/20 0.51
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
APP P05067 1/20 0.49
ABL1 P00519 1/20 0.49
ABCB1 P08183 1/20 0.49
BCR P11274 1/20 0.49
NPC1 O15118 1/20 0.49
TP53 P04637 1/20 0.49
MAPK1 P28482 1/20 0.49
CASP3 P42574 1/20 0.49
RAB9A P51151 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19018111 0.95 PKM (0.89) PKMGAALTA4HESR2ELANE
SCHEMBL12780829 0.91 PKM (0.63) PKMGAALTA4HESR2ELANE
SCHEMBL14456654 0.91 PKM (0.76) PKMGAAKDM4EALDH1A1SMN1; SMN2
SCHEMBL14463488 0.91 PKM (0.63) PKMGAALTA4HESR2ELANE
SCHEMBL828851 0.89 PKM (1.00) PKMGAALTA4HESR2ELANE
SCHEMBL16425838 0.87 HTT (0.65) PKMGAALTA4HESR2ELANE
SCHEMBL16588321 0.87 HTT (0.65) PKMGAALTA4HESR2ELANE
SCHEMBL14265612 0.87 HTT (0.65) PKMGAALTA4HESR2ELANE
SCHEMBL12954962 0.87 HTT (0.65) PKMGAALTA4HESR2ELANE
SCHEMBL15315940 0.87 HTT (0.65) PKMGAALTA4HESR2ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12023558-B2 Golf club heads TAYLOR MADE GOLF COMPANY, INC. (US) 2024-07-02 US disclosed
US-20230218956-A1 GOLF CLUB HEAD TAYLOR MADE GOLF COMPANY, INC. 2023-07-13 US disclosed