SCHEMBL828851

SCHEMBL828851

COc1ccc(S(=O)(=O)c2ccc(O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 1.00
GAA P10253 1/20 1.00
ELANE P08246 2/20 0.61
LTA4H P09960 1/20 0.59
ESR2 Q92731 1/20 0.59
HSD11B1 P28845 1/20 0.56
CA2 P00918 2/20 0.55
CA1 P00915 1/20 0.55
MMP1 P03956 1/20 0.55
MMP2 P08253 1/20 0.55
MMP9 P14780 1/20 0.55
MMP8 P22894 1/20 0.55
MMP13 P45452 1/20 0.55
APP P05067 1/20 0.53
RAPGEF4 Q8WZA2 1/20 0.53
POLB P06746 1/20 0.52
MAPT P10636 1/20 0.52
CYTH2 Q99418 1/20 0.51
TUBB4A P04350 1/20 0.51
TUBB P07437 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19018111 0.94 PKM (0.89) PKMGAAELANELTA4HESR2
SCHEMBL25922128 0.89 PKM (0.80) PKMGAAELANELTA4HESR2
SCHEMBL14486413 0.89 PKM (1.00) PKMGAAHSD11B1CA2CA1
SCHEMBL13074716 0.89 PKM (1.00) PKMGAAHSD11B1CA2CA1
SCHEMBL835692 0.89 PKM (1.00) PKMGAAHSD11B1CA2CA1
SCHEMBL537312 0.88 PKM (0.77) PKMGAAELANELTA4HESR2
SCHEMBL16775430 0.88 GAA (0.77) PKMGAAELANELTA4HESR2
SCHEMBL7753235 0.87 PKM (0.75) PKMGAAAPPPOLBMAPT
Mequinol SCHEMBL28697292 0.85 PKM (0.74) PKMGAALTA4HESR2CA2
Mequinol SCHEMBL23541071 0.85 PKM (0.73) PKMGAALTA4HESR2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6344671-A None JP disclosed
JP-3216381-A None JP disclosed
JP-3173689-A None JP disclosed
US-12030328-B2 Thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2024-07-09 US disclosed
EP-3395583-B1 HEAT-SENSITIVE RECORDING MATERIAL NIPPON KAYAKU KK (JP) 2024-03-27 EP disclosed
US-20240069441-A1 COMPOSITION FOR RESIST UNDERLYING FILM FORMATION NISSAN CHEMICAL CORPORATION (JP) 2024-02-29 US disclosed
US-20240069441-A1 COMPOSITION FOR RESIST UNDERLYING FILM FORMATION NISSAN CHEMICAL CORPORATION (JP) 2024-02-29 US disclosed
US-20240019779-A1 COMPOUNDS AND PHOTORESIST COMPOSITIONS INCLUDING THE SAME U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-01-18 US disclosed
US-11815815-B2 Composition for forming silicon-containing resist underlayer film removable by wet process NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-11815815-B2 Composition for forming silicon-containing resist underlayer film removable by wet process NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-4616239-A 4-hydroxy-4'-isopropoxydiphenylsulfone and its use for color-developable recording material SHIN NISSO KAKO CO., LTD. (JP) 1986-10-07 US disclosed
US-4611072-A Heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1986-09-09 US disclosed
EP-0179492-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1986-04-30 EP disclosed
US-4568766-A HEAT-SENSITIVE MATERIAL NIPPON SODA COMPANY LIMITED (JP) 1986-02-04 US disclosed
US-4536779-A PHENOLSULFONYL SALT AS DEVELOPER FOR COLOR FORMER CIBA-GEIGY CORPORATION (US) 1985-08-20 US disclosed
EP-0067793-B1 PRESSURE OR HEAT SENSITIVE RECORDING MATERIALS CIBA-GEIGY AG (CH) 1985-04-17 EP disclosed
EP-0112291-A2 Heat-sensitive registration material CIBA-GEIGY AG (CH) 1984-06-27 EP disclosed
US-4453744-A Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1984-06-12 US disclosed
EP-0067793-A2 Pressure or heat sensitive recording materials CIBA-GEIGY AG (CH) 1982-12-22 EP disclosed
US-4101323-A Radiation-sensitive copying composition HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240019779-A1 COMPOUNDS AND PHOTORESIST COMPOSITIONS INCLUDING THE SAME CRY1, CCNT1, CCNA1 PKM 1050/4885GAA 3580/4885ELANE 1993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.