Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26622776 | 0.80 | APLNR (0.39) | NUDT1CCNA2CDK2CCNA1CDK5 | |
| SCHEMBL25316534 | 0.80 | NUDT1 (0.32) | NUDT1CCNA2CDK2CCNA1CDK5 | |
| SCHEMBL14595286 | 0.78 | NUDT1 (0.38) | NUDT1CCNA2CDK2CCNA1CDK5 | |
| SCHEMBL18149303 | 0.78 | KDM4E (0.32) | NUDT1CCNA2CDK2CCNA1CDK5 | |
| SCHEMBL25922712 | 0.75 | NUDT1 (0.33) | NUDT1CCNA2CDK2CCNA1CDK5 | |
| SCHEMBL22663608 | 0.74 | — | — | |
| SCHEMBL26029081 | 0.67 | TDP1 (0.41) | — | |
| SCHEMBL25315994 | 0.67 | FFAR1 (0.46) | — | |
| SCHEMBL22313139 | 0.64 | NUDT1 (0.31) | NUDT1 | |
| SCHEMBL17619921 | 0.64 | TRPV4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |