Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24673819 | 0.87 | L3MBTL1 (0.44) | L3MBTL1LMNAOPRM1OPRK1CA2 | |
| SCHEMBL22856392 | 0.84 | L3MBTL1 (0.46) | L3MBTL1GAAMAPTLMNAOPRM1 | |
| SCHEMBL22794506 | 0.84 | TAAR1 (0.50) | L3MBTL1GAAMAPTLMNAOPRM1 | |
| SCHEMBL21655058 | 0.83 | L3MBTL1 (0.53) | L3MBTL1LMNAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL23945588 | 0.83 | L3MBTL1 (0.42) | L3MBTL1GAAMAPTOPRM1OPRK1 | |
| SCHEMBL23945721 | 0.82 | L3MBTL1 (0.45) | L3MBTL1GAAMAPTLMNAOPRM1 | |
| SCHEMBL25883717 | 0.81 | L3MBTL1 (0.44) | L3MBTL1GAAMAPTOPRM1OPRK1 | |
| SCHEMBL25479303 | 0.81 | LMNA (0.57) | L3MBTL1GAAMAPTLMNAOPRM1 | |
| SCHEMBL2242597 | 0.78 | TAAR1 (0.52) | L3MBTL1OPRM1OPRK1CA2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28573233 | 0.78 | SIGMAR1 (0.42) | L3MBTL1GAAMAPTCA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234953-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234953-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | L3MBTL1 1394/4885GAA 1234/4885MAPT 2459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.