SCHEMBL2592399

SCHEMBL2592399

O=C(OOC(=O)C(F)(F)C(F)F)C(F)(F)C(F)F

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.38
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1405131 0.82 PKM (0.38) PKMKDM4ETSHRTDP1
SCHEMBL8386054 0.81 ALDH1A1 (0.34) PKMTSHRTDP1
SCHEMBL503350 0.80 PKM (0.37) PKM
SCHEMBL28176606 0.78 PKM (0.35) PKM
SCHEMBL10622484 0.78 ALDH1A1 (0.33) TSHR
SCHEMBL4020329 0.78
SCHEMBL898549 0.78 PKM (0.40) PKM
SCHEMBL19915241 0.78 PKM (0.35) PKM
SCHEMBL10496264 0.78 PKM (0.35) PKM
SCHEMBL25413841 0.76 PKM (0.34) PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8883935-B2 High refractive index composition BATTELLE MEMORIAL INSTITUTE (US) 2014-11-11 US disclosed
EP-2563826-A2 HIGH REFRACTIVE INDEX COMPOSITION Battelle Memorial Institute (US) 2013-03-06 EP disclosed
US-20130046054-A1 HIGH REFRACTIVE INDEX COMPOSITION BATTELLE MEMORIAL INSTITUTE (US) 2013-02-21 US disclosed
WO-2011139856-A2 HIGH REFRACTIVE INDEX COMPOSITION BATTELLE MEMORIAL INSTITUTE (US) 2011-11-10 WO disclosed
US-6491903-B1 NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY WASHINGTON UNIVERSITY 2002-12-10 US disclosed
US-6383500-B1 Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications WASHINGTON UNIVERSITY 2002-05-07 US disclosed
EP-0709428-B1 THERMOPLASTIC RESIN COMPOSITION DAIKIN IND LTD (JP) 1999-07-07 EP disclosed
US-5767198-A Thermoplastic resin composition DAIKIN INDUSTRIES, LTD. (JP) 1998-06-16 US disclosed
EP-0709428-A1 THERMOPLASTIC RESIN COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 1996-05-01 EP disclosed
US-4116888-A Process for producing fluorinated copolymer having ion-exchange groups ASAHI GLASS COMPANY LTD. (JP) 1978-09-26 US disclosed