SCHEMBL898549

SCHEMBL898549

COC(=O)C(F)(F)C(F)F

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.40
CTRB1 P17538 1/20 0.39
DGAT1 O75907 1/20 0.36
ALDH1A1 P00352 2/20 0.35
KCNN4 O15554 1/20 0.32
GAA P10253 1/20 0.30
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL28769040 0.97 PKM (0.39) PKMCTRB1DGAT1ALDH1A1KCNN4
SCHEMBL21375478 0.84 CTRB1 (0.39) PKMCTRB1DGAT1ALDH1A1KCNN4
SCHEMBL11216608 0.84 CTRB1 (0.39) PKMCTRB1DGAT1ALDH1A1KCNN4
SCHEMBL10601712 0.82 CTRB1 (0.38) PKMCTRB1DGAT1ALDH1A1KCNN4
SCHEMBL17067292 0.81 CTRB1 (0.40) CTRB1DGAT1ALDH1A1KCNN4GAA
SCHEMBL503350 0.81 PKM (0.37) PKM
SCHEMBL20817069 0.80 POLB (0.39) CTRB1ALDH1A1GAA
SCHEMBL10496264 0.79 PKM (0.35) PKM
SCHEMBL765780 0.79 DGAT1 (0.41) CTRB1DGAT1ALDH1A1KCNN4
SCHEMBL19915241 0.79 PKM (0.35) PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102880-A1 FULL-TEMPERATURE-RANGE POLYMER-BASED SOLID ELECTROLYTE, SOLID-STATE BATTERY AND PREPARATION METHOD 固态离子能源科技(武汉)有限公司 2026-05-21 WO claimed
CN-119490607-A Full-temperature-range polymer-based solid electrolyte, solid battery and preparation method 固态离子能源科技(武汉)有限公司 2025-02-21 CN claimed
CN-118040044-A Electrolyte additive, electrolyte and lithium ion battery 南昌大学 2024-05-14 CN claimed
CN-117613372-A Secondary battery and electricity utilization device 欣旺达动力科技股份有限公司 2024-02-27 CN claimed
CN-116253861-B Spraying airtight plugging polyurethane foam and preparation method thereof 北京北开中电电气设备有限公司 2023-08-08 CN claimed
CN-116315071-A Wide-temperature solid electrolyte 上海交通大学绍兴新能源与分子工程研究院 2023-06-23 CN claimed
CN-116253861-A Spraying airtight plugging polyurethane foam and preparation method thereof 北京北开中电电气设备有限公司 2023-06-13 CN claimed
EP-2978756-B1 SUBSTITUTED OXOPYRIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CARDIOVASCULAR DISEASES Bayer Pharma AG (DE) 2019-03-27 EP claimed
US-10138236-B2 Factor xia-inhibiting pyridobenzazepine and pyridobenzazocine derivatives BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-11-27 US claimed
EP-3197891-B1 FACTOR XIA-INHIBITING PYRIDOBENZAZEPINE AND PYRIDOBENZAZOCINE DERIVATIVES Bayer Pharma AG (DE) 2018-11-21 EP claimed
EP-3024822-B1 SUBSTITUTED OXOPYRIDINE DERIVATIVES AND THEIR USE AS FACTOR XIA AND PLASMA KALLIKREIN INHIBITORS Bayer Pharma AG (DE) 2017-05-03 EP claimed
US-20170035739-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES AND USE THEREOF AS FACTOR XIA/PLASMA BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2017-02-09 US claimed
US-9475809-B2 Substituted oxopyridine derivatives and use thereof as factor xia/plasma BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-10-25 US claimed
US-9434690-B2 Substituted oxopyridine derivatives and use thereof in the treatment of cardiovascular disorders BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-09-06 US claimed
US-20160152613-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES AND USE THEREOF AS FACTOR XIA/PLASMA BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-06-02 US claimed
US-20160052884-A1 Substituted Oxopyridine Derivatives and Use Thereof in the Treatment of Cardiovascular Disorders BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-02-25 US claimed
EP-2978756-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF CARDIOVASCULAR DISORDERS Bayer Pharma Aktiengesellschaft (DE) 2016-02-03 EP claimed
WO-2014154794-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF CARDIOVASCULAR DISORDERS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2014-10-02 WO claimed
US-20140227611-A1 Non-Aqueous Secondary Battery NEC CORPORATION (JP) 2014-08-14 US claimed
US-5336801-A Reacting a cyanide salt, water and tetrafluoroethylene in the presence of an acyclic alcohol E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-08-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160152613-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES AND USE THEREOF AS FACTOR XIA/PLASMA F11, F2, F10 PKM 1449/4885CTRB1 1784/4885DGAT1 4099/4885
US-10138236-B2 Factor xia-inhibiting pyridobenzazepine and pyridobenzazocine derivatives F13B, TFPI, TFPI2 PKM 1482/4885CTRB1 127/4885DGAT1 4575/4885
US-20160052884-A1 Substituted Oxopyridine Derivatives and Use Thereof in the Treatment of Cardiovascular Disorders OGFOD1, PNPO, VASP PKM 653/4885CTRB1 3327/4885DGAT1 2736/4885
US-20170035739-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES AND USE THEREOF AS FACTOR XIA/PLASMA F11, F2, F10 PKM 1449/4885CTRB1 1784/4885DGAT1 4099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.