Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 10/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389620 | 0.77 | KDM4E (0.47) | KDM4EKDM4DFGFR1FGFR4 | |
| SCHEMBL25924153 | 0.70 | CNR2 (0.36) | CNR2CNR1 | |
| SCHEMBL256383 | 0.68 | KDM4E (0.55) | KDM4EKDM4DFGFR1FGFR4MTNR1A | |
| SCHEMBL20812401 | 0.67 | CRBN (0.67) | — | |
| SCHEMBL30855654 | 0.67 | ALDH1A1 (0.45) | KDM4ECNR2CNR1 | |
| SCHEMBL29401523 | 0.66 | ALDH1A1 (0.44) | KDM4ECNR2CNR1 | |
| SCHEMBL29311590 | 0.65 | KDM4E (0.36) | KDM4EKDM4D | |
| SCHEMBL25316447 | 0.65 | CNR2 (0.45) | CNR2 | |
| SCHEMBL3375873 | 0.64 | KDM4E (0.55) | KDM4EKDM4DFGFR1FGFR4 | |
| SCHEMBL21089903 | 0.64 | KDM4E (0.59) | KDM4EKDM4DFGFR1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |