Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 4/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ABL2 | P42684 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25924159 | 0.77 | KDM4E (0.43) | KDM4EFGFR1FGFR4KDM4D | |
| SCHEMBL31389534 | 0.76 | DDB1 (0.44) | MAPK8MAPK9MAPK10 | |
| SCHEMBL28642847 | 0.75 | KDM5A (0.32) | LRRK2 | |
| SCHEMBL31389449 | 0.71 | ADRA2A (0.46) | KDM4EMAPK8MAPK9MAPK10LRRK2 | |
| SCHEMBL7008753 | 0.69 | KDM4E (0.55) | KDM4EFGFR1FGFR4KDM4DPARP1 | |
| SCHEMBL30855654 | 0.68 | ALDH1A1 (0.45) | KDM4E | |
| SCHEMBL25207260 | 0.68 | LRRK2 (0.31) | LRRK2 | |
| SCHEMBL31389453 | 0.67 | KDM4E (0.39) | KDM4ERETKDRLRRK2PDE4B | |
| SCHEMBL29401523 | 0.67 | ALDH1A1 (0.44) | KDM4E | |
| SCHEMBL25317289 | 0.66 | HTR2A (0.35) | LRRK2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |