Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.43 |
| ▸ | LPL | P06858 | 7/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28989321 | 0.83 | ESR2 (0.53) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28989322 | 0.83 | ESR2 (0.53) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL17289557 | 0.81 | F11 (0.42) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL17289554 | 0.81 | F11 (0.42) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL29248322 | 0.78 | F11 (0.40) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL16501554 | 0.77 | ESR2 (0.52) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1317427 | 0.76 | ADRA2B (0.51) | — | |
| SCHEMBL2578174 | 0.76 | MME (0.47) | — | |
| SCHEMBL2595120 | 0.74 | LIPG (0.52) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1290119 | 0.74 | LIPG (0.51) | F11F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123419-A1 | TRYCYCLIC COMPOUNDS AND PBK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2011-10-06 | — | — | WO | disclosed |