Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29468655 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL777548 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL6937363 | 0.80 | ALDH1A1 (0.45) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL30821607 | 0.80 | ALDH1A1 (0.45) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL777549 | 0.78 | SLC22A6 (0.46) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL28967200 | 0.78 | ELANE (0.59) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL3372383 | 0.78 | CA2 (0.52) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL13752372 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL14861976 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL17456550 | 0.77 | SLC22A6 (0.44) | ALDH1A1LMNAMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781165-B2 | Benzimidazolium compounds and salts of benzimidazolium compounds for nucleic acid amplification | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| US-20100184973-A1 | Method for producing dioxazine derivatives | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
| EP-1777300-B1 | Organic salt additives for nucleic acid amplification | ROCHE DIAGNOSTICS GMBH (DE) | 2008-08-27 | — | — | EP | disclosed |
| US-20070099220-A1 | Organic salt additives for nucleic acid amplification | ROCHE DIAGNOSTICS GMBH (DE) | 2007-05-03 | — | — | US | disclosed |
| EP-1777300-A1 | Organic salt additives for nucleic acid amplification | Roche Diagnostics GmbH (DE) | 2007-04-25 | — | — | EP | disclosed |
| EP-0499282-B1 | Aqueous concentrate of at least one alkyl- or alkenyl substituted ammonium compound | HOECHST AG (DE) | 1995-07-05 | — | — | EP | disclosed |
| EP-0499282-A1 | Aqueous concentrate of at least one alkyl- or alkenyl substituted ammonium compound | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-19 | — | — | EP | disclosed |
| US-4404230-A | ARTICIFIAL SWEETENERS | DR. KARL THOMAE GMBH (DE) | 1983-09-13 | — | — | US | disclosed |
| US-4388246-A | THERMAL SPLITTING OF CARBAMATES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099220-A1 | Organic salt additives for nucleic acid amplification | POLN, NSUN3, POLRMT | ALDH1A1 2440/4885LMNA 405/4885MEN1 3128/4885 |
| US-20100184973-A1 | Method for producing dioxazine derivatives | CYP4Z1, CYP1A1, CYP2F1 | ALDH1A1 127/4885LMNA 2336/4885MEN1 1980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.