Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26023919 | 0.79 | DRD2 (0.36) | DRD2DRD3OPRM1OPRL1ALDH1A1 | |
| SCHEMBL25924497 | 0.78 | KRAS (0.34) | DRD2DRD3OPRM1OPRL1ALDH1A1 | |
| SCHEMBL26023918 | 0.76 | DRD2 (0.34) | DRD2DRD3OPRM1OPRL1ALDH1A1 | |
| SCHEMBL26023916 | 0.76 | DRD2 (0.34) | DRD2DRD3OPRM1OPRL1ALDH1A1 | |
| SCHEMBL25317133 | 0.69 | PRPS1 (0.36) | DRD2DRD3OPRM1OPRL1CYP2C9 | |
| SCHEMBL25924467 | 0.69 | PRPS1 (0.36) | DRD2DRD3OPRM1OPRL1CYP2C9 | |
| SCHEMBL30507264 | 0.69 | PRPS1 (0.36) | DRD2DRD3OPRM1OPRL1CYP2C9 | |
| SCHEMBL31415669 | 0.68 | AR (0.43) | DRD2DRD3OPRM1OPRL1CYP2C9 | |
| SCHEMBL26023928 | 0.65 | — | — | |
| SCHEMBL26023927 | 0.63 | CNR2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |