Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 4/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | TTK | P33981 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | MAP3K7 | O43318 | 3/20 | 0.40 |
| ▸ | TAB1 | Q15750 | 3/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25924807 | 0.88 | TNK2 (0.46) | TNK2JAK2JAK3PTK2MET | |
| SCHEMBL25925229 | 0.85 | EGFR (0.39) | METEGFRHTR6MAP3K7TAB1 | |
| SCHEMBL25924724 | 0.83 | MET (0.38) | METEGFRHTR6MAP3K7TAB1 | |
| SCHEMBL25924720 | 0.83 | CYP1A2 (0.48) | JAK2METMAP3K7TAB1 | |
| SCHEMBL24723202 | 0.82 | MET (0.48) | TNK2JAK2JAK3PTK2MET | |
| SCHEMBL16698398 | 0.79 | MET (0.48) | TNK2JAK2JAK3PTK2MET | |
| SCHEMBL16268256 | 0.79 | MET (0.52) | TNK2JAK2JAK3PTK2MET | |
| SCHEMBL30934901 | 0.78 | DYRK1A (0.40) | TNK2JAK2JAK3PTK2MET | |
| SCHEMBL16267900 | 0.78 | MET (0.48) | TNK2JAK2JAK3PTK2MET | |
| SCHEMBL2283400 | 0.76 | PDPK1 (0.42) | CCNCCDK8HTR6FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131271-A1 | PYRROLE FUSED-RING PYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2023-07-13 | — | — | WO | disclosed |