Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.63 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4333117 | 0.85 | LOXL2 (0.59) | LOXL2AOC3HRH3AHRHRH4 | |
| SCHEMBL5642064 | 0.82 | LOXL2 (0.60) | LOXL2AOC3HRH3AHRHRH4 | |
| SCHEMBL2592547 | 0.82 | LOXL2 (0.60) | LOXL2AOC3HRH3AHRHRH4 | |
| SCHEMBL7549813 | 0.81 | LOXL2 (0.59) | LOXL2AOC3HRH3AHRHRH4 | |
| SCHEMBL7355775 | 0.81 | LOXL2 (0.59) | LOXL2AOC3HRH3AHRHRH4 | |
| SCHEMBL325463 | 0.81 | LOXL2 (0.58) | LOXL2AOC3HRH3AHRHRH4 | |
| SCHEMBL2485760 | 0.81 | LOXL2 (0.58) | LOXL2AOC3HRH3AHRHRH4 | |
| SCHEMBL108898 | 0.81 | LOXL2 (0.58) | LOXL2AOC3HRH3AHRHRH4 | |
| SCHEMBL31105584 | 0.81 | LOXL2 (0.58) | LOXL2AOC3HRH3AHRHRH4 | |
| SCHEMBL29796415 | 0.81 | LOXL2 (0.58) | LOXL2AOC3HRH3AHRHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230104311-A1 | NOVEL 6-SUBSTITUTED 7-DEAZAPURINES AND CORRESPONDING NUCLEOSIDES AS MEDICAMENTS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-04-06 | — | — | US | disclosed |
| EP-4106763-A1 | NOVEL 6-SUBSTITUTED 7-DEAZAPURINES AND CORRESPONDING NUCLEOSIDES AS MEDICAMENTS | Katholieke Universiteit Leuven KU Leuven Research & Development (BE) | 2022-12-28 | — | — | EP | disclosed |
| CN-115515593-A | Novel 6-substituted 7-deazapurines and corresponding nucleosides as medicaments | 勒芬天主教大学 | 2022-12-23 | — | — | CN | disclosed |
| EP-2864312-B1 | NOVEL ANTI-CANCER THIOPHENE COMPOUNDS | UNIV LEUVEN KATH (BE) | 2021-09-22 | — | — | EP | disclosed |
| US-20210276988-A1 | 4,6-DI- AND 2,4,6-TRISUBSTITUTED QUINAZOLINE DERIVATIVES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. | 2021-09-09 | — | — | US | disclosed |
| US-10882851-B2 | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections | GILEAD SCIENCES, INC. (US) | 2021-01-05 | — | — | US | disclosed |
| US-20190152974-A1 | SUBSTITUTED PTERIDINES USEFUL FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS | GILEAD SCIENCES, INC. | 2019-05-23 | — | — | US | disclosed |
| US-10144736-B2 | Substituted pteridines useful for the treatment and prevention of viral infections | GILEAD SCIENCES, INC. (US) | 2018-12-04 | — | — | US | disclosed |
| EP-2923734-B1 | PURINE ANALOGUES AND THEIR USE AS IMMUNOSUPPRESSIVE AGENTS | UNIV LEUVEN KATH (BE) | 2018-01-10 | — | — | EP | disclosed |
| US-9822127-B2 | GAK modulators as antivirals | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-11-21 | — | — | US | disclosed |
| EP-1577282-A2 | Metal complexes for use in olefin methathesis and atom or group transfer reactions | Universiteit Gent (BE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2005084529-A2 | METHOD OF DETERMINING THE SYMPATHETIC TONE AND SYSTEM FOR MEASUREMENT THEREOF | STRESSMETER A/S (DK) | 2005-09-15 | — | — | WO | disclosed |
| WO-2005085268-A2 | PHOSPONATE NUCLEOSIDES USEFUL AS ACTIVE INGREDIENTS IN PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS, AND INTERMEDIATES FOR THEIR PRODUCTION | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2005-09-15 | — | — | WO | disclosed |
| US-20050159581-A1 | Method of preparing derivatives of polyarylene vinylene and method of preparing an electronic device including same | LIMBURGS UNIVERSITAIR CENTRUM (BE) | 2005-07-21 | — | — | US | disclosed |
| EP-1548044-A2 | Method of preparing derivatives of polyarylene vinylene and method of preparing an electronic device including same | INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM VZW (BE) | 2005-06-29 | — | — | EP | disclosed |
| EP-1529794-A1 | Method of preparing derivatives of polyarylene vinylene and method of preparing an electronic device including same | INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM VZW (BE) | 2005-05-11 | — | — | EP | disclosed |
| WO-2005039587-A1 | HETEROCYCLE-SUBSTITUTED PTERIDINE DERIVATIVES AND THEIR USE IN THERAPY | 4 AZA BIOSCIENCE NV (BE) | 2005-05-06 | — | — | WO | disclosed |
| WO-2005035121-A2 | SCHIFF BASE METAL COMPLEXES FOR USE AS CATALYSTS IN ORGANIC SYNTHESIS | UNIVERSITEIT GENT (BE) | 2005-04-21 | — | — | WO | disclosed |
| US-20050043541-A1 | Metal complexes useful in metathesis and other reactions | RIMTEC CORPORATION (JP) | 2005-02-24 | — | — | US | disclosed |
| WO-2004104005-A2 | IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | 4 AZA BIOSCIENCE NV (BE) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043541-A1 | Metal complexes useful in metathesis and other reactions | TST, ETFA, TTPA | LOXL2 3336/4885AOC3 321/4885HRH3 4652/4885 |
| US-20210276988-A1 | 4,6-DI- AND 2,4,6-TRISUBSTITUTED QUINAZOLINE DERIVATIVES USEFUL FOR TREATING VIRAL INFECTIONS | NR3C1, NR3C2, NR4A1 | LOXL2 2084/4885AOC3 798/4885HRH3 168/4885 |
| US-20190152974-A1 | SUBSTITUTED PTERIDINES USEFUL FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS | HCCS, DPYD, HAVCR2 | LOXL2 4397/4885AOC3 2466/4885HRH3 1589/4885 |
| US-10144736-B2 | Substituted pteridines useful for the treatment and prevention of viral infections | HCCS, DPYD, HAVCR2 | LOXL2 4397/4885AOC3 2466/4885HRH3 1589/4885 |
| US-20230104311-A1 | NOVEL 6-SUBSTITUTED 7-DEAZAPURINES AND CORRESPONDING NUCLEOSIDES AS MEDICAMENTS | ADA, ADAR, TPMT | LOXL2 4491/4885AOC3 47/4885HRH3 2908/4885 |
| US-10882851-B2 | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections | NR3C1, NR3C2, NR5A2 | LOXL2 3514/4885AOC3 1064/4885HRH3 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.