Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 8/20 | 0.43 |
| ▸ | BRD2 | P25440 | 2/20 | 0.43 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25330749 | 0.84 | BRD4 (0.44) | BRD4BRD9BRD2BRD7CREBBP | |
| SCHEMBL25925478 | 0.78 | BRD4 (0.43) | BRD4BRD9BRD2BRD7CREBBP | |
| SCHEMBL25925473 | 0.77 | BRD4 (0.48) | BRD4BRD9BRD2BRD7CREBBP | |
| SCHEMBL25925604 | 0.70 | BRD9 (0.65) | BRD4BRD9BRD2BRD7CREBBP | |
| SCHEMBL25925462 | 0.69 | BRD4 (0.48) | BRD4BRD9BRD2BRD7CREBBP | |
| SCHEMBL9323197 | 0.69 | ALDH1A1 (0.54) | — | |
| SCHEMBL21224833 | 0.68 | BRD4 (0.54) | BRD4BRD9BRD2BRD7CREBBP | |
| SCHEMBL23134699 | 0.67 | BRD4 (0.68) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL22251112 | 0.67 | BRD4 (0.35) | BRD4BRD9BRD2BRD7CREBBP | |
| SCHEMBL25925481 | 0.66 | BRD9 (0.41) | BRD4BRD9BRD2BRD7CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109892-A1 | COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |