Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.45 |
| ▸ | F2 | P00734 | 5/20 | 0.45 |
| ▸ | PLAU | P00749 | 5/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25925598 | 0.90 | ELANE (0.46) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL19208662 | 0.89 | ELANE (0.46) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL29781526 | 0.89 | ELANE (0.46) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL19208691 | 0.85 | ELANE (0.53) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL25925602 | 0.82 | CNR1 (0.44) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL29781710 | 0.81 | ELANE (0.48) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL19208461 | 0.81 | ELANE (0.48) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL25926051 | 0.81 | CFD (0.44) | ELANEPLA2G2A | |
| SCHEMBL25925489 | 0.81 | CFD (0.44) | ELANEPLA2G2A | |
| SCHEMBL11153043 | 0.81 | LMNA (0.46) | ELANEF2PLAUCTRB1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218578-A1 | BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218578-A1 | BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF | C9, C5, C1QBP | ELANE 119/4885F2 28/4885PLAU 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.