Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.42 |
| ▸ | MTOR | P42345 | 3/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.35 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 2/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25925650 | 0.85 | FFAR2 (0.35) | LRRK2FFAR2MAP3K12 | |
| SCHEMBL2712251 | 0.85 | PIK3CA (0.44) | PIK3CAMTORC5AR1LATS1LRRK2 | |
| SCHEMBL12235999 | 0.83 | PIK3CA (0.47) | PIK3CAMTORC5AR1LATS1LRRK2 | |
| SCHEMBL25931435 | 0.83 | LRRK2 (0.44) | PIK3CAMTORC5AR1LATS1LRRK2 | |
| SCHEMBL25930722 | 0.80 | PIK3CA (0.37) | PIK3CAMTORLATS1LRRK2PDE10A | |
| SCHEMBL2712256 | 0.80 | ALDH1A1 (0.45) | PIK3CAMTORLATS1LRRK2SCN10A | |
| SCHEMBL1707795 | 0.79 | ALDH1A1 (0.44) | PIK3CAMTORLRRK2PDE10A | |
| SCHEMBL25925717 | 0.78 | PIK3CA (0.39) | PIK3CAMTORC5AR1LATS1LRRK2 | |
| SCHEMBL26040948 | 0.75 | OPRK1 (0.36) | PDE10A | |
| SCHEMBL25932310 | 0.74 | LATS1 (0.41) | PIK3CAMTORC5AR1LATS1FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131271-A1 | PYRROLE FUSED-RING PYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2023-07-13 | — | — | WO | disclosed |