Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CPN1 | P15169 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | APLNR | P35414 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2550008 | 0.81 | — | — | |
| SCHEMBL15973100 | 0.77 | ADH1B (0.34) | — | |
| Formic Acid SCHEMBL28509174 | 0.77 | CPN1 (0.42) | EPHX1CPN1CPB2SLC6A1SLC6A11 | |
| SCHEMBL15974686 | 0.73 | — | — | |
| SCHEMBL22420915 | 0.71 | SLC6A1 (0.37) | SLC6A1SLC6A11SLC6A13TSHRLMNA | |
| SCHEMBL10045710 | 0.70 | — | — | |
| Formic Acid SCHEMBL28681473 | 0.70 | SLC6A1 (0.42) | EPHX1CPN1CPB2SLC6A1SLC6A11 | |
| SCHEMBL25455590 | 0.69 | — | — | |
| SCHEMBL21686127 | 0.69 | — | — | |
| SCHEMBL27048229 | 0.68 | EPHX2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219449-A2 | SUBSTITUTED INDOLE DERIVATIVES AND METHODS OF PREPARATION THEREOF | Kura Oncology, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |