SCHEMBL25926916

SCHEMBL25926916

O=c1c(O)c(-c2cc(O)c(O)c(O)c2)oc2cc(O)c(O)c(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 2/20 1.00
CD38 P28907 4/20 0.77
AMY1A P0DUB6 3/20 0.77
PIM1 P11309 3/20 0.77
MEN1 O00255 8/20 0.71
KMT2A Q03164 8/20 0.71
CYP3A4 P08684 6/20 0.71
TDP1 Q9NUW8 5/20 0.71
RECQL P46063 5/20 0.71
KDM4E B2RXH2 5/20 0.71
ALOX15 P16050 5/20 0.71
HSD17B10 Q99714 5/20 0.71
MAPT P10636 5/20 0.71
CYP1A2 P05177 5/20 0.71
CYP2C9 P11712 5/20 0.71
ABCC1 P33527 4/20 0.71
ALDH1A1 P00352 4/20 0.71
HPGD P15428 4/20 0.71
HIF1A Q16665 4/20 0.71
CYP1A1 P04798 4/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quercetagetin SCHEMBL29608135 0.87 AMY1A (1.00) MAPK8CD38AMY1APIM1MEN1
Quercetagetin SCHEMBL554527 0.87 AMY1A (1.00) MAPK8CD38AMY1APIM1MEN1
SCHEMBL1883826 0.87 MAPK8 (0.77) MAPK8CD38AMY1APIM1MEN1
Quercetagetin SCHEMBL29690479 0.87 AMY1A (1.00) MAPK8CD38AMY1APIM1MEN1
6-Hydroxykaempferol SCHEMBL674949 0.85 AMY1A (0.76) MAPK8CD38AMY1APIM1MEN1
SCHEMBL157972 0.85 MAPK8 (0.74) MAPK8CD38AMY1APIM1MEN1
6-Hydroxykaempferol SCHEMBL29725747 0.85 AMY1A (0.76) MAPK8CD38AMY1APIM1MEN1
SCHEMBL7120515 0.84 MAPK8 (0.71) MAPK8CD38AMY1APIM1MEN1
SCHEMBL26255803 0.84 AMY1A (0.77) MAPK8CD38AMY1APIM1MEN1
Myricetin SCHEMBL19302 0.83 MEN1 (1.00) MAPK8CD38AMY1APIM1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230194990-A1 PHOTORESIST UNDERLAYER COMPOSITION U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-06-22 US disclosed
US-20230194990-A1 PHOTORESIST UNDERLAYER COMPOSITION U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-06-22 US disclosed