Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.77 |
| ▸ | PIM1 | P11309 | 3/20 | 0.77 |
| ▸ | CD38 | P28907 | 3/20 | 0.77 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.56 |
| ▸ | XDH | P47989 | 6/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | IPMK | Q8NFU5 | 5/20 | 0.56 |
| ▸ | IP6K2 | Q9UHH9 | 5/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.56 |
| ▸ | RECQL | P46063 | 4/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quercetagetin SCHEMBL29608135 | 0.87 | AMY1A (1.00) | AMY1APIM1CD38MAPK8MEN1 | |
| Quercetagetin SCHEMBL29690479 | 0.87 | AMY1A (1.00) | AMY1APIM1CD38MAPK8MEN1 | |
| Quercetagetin SCHEMBL554527 | 0.87 | AMY1A (1.00) | AMY1APIM1CD38MAPK8MEN1 | |
| Quercetagetin SCHEMBL7647221 | 0.85 | AMY1A (0.89) | AMY1APIM1CD38MAPK8MEN1 | |
| SCHEMBL9288825 | 0.85 | MEN1 (0.78) | AMY1APIM1CD38MEN1KMT2A | |
| Quercetagetin SCHEMBL28164757 | 0.84 | AMY1A (0.87) | AMY1APIM1CD38MAPK8MEN1 | |
| SCHEMBL25926916 | 0.84 | MAPK8 (1.00) | AMY1APIM1CD38MAPK8MEN1 | |
| 6-Hydroxykaempferol SCHEMBL29725747 | 0.82 | AMY1A (0.76) | AMY1APIM1CD38MAPK8MEN1 | |
| 6-Hydroxykaempferol SCHEMBL674949 | 0.82 | AMY1A (0.76) | AMY1APIM1CD38MAPK8MEN1 | |
| SCHEMBL26621024 | 0.81 | MGAM (0.73) | MEN1KMT2AKDM4ECYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11759530-B2 | TKI permeability enhancers | CITY OF HOPE (US) | 2023-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11759530-B2 | TKI permeability enhancers | ABL1, TK1, EGFR | AMY1A 4782/4885PIM1 274/4885CD38 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.