Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.71 |
| ▸ | MAOA | P21397 | 3/20 | 0.62 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.60 |
| ▸ | PIM1 | P11309 | 2/20 | 0.60 |
| ▸ | CD38 | P28907 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | IPMK | Q8NFU5 | 3/20 | 0.60 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | APP | P05067 | 2/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 2/20 | 0.60 |
| ▸ | ELAVL3 | Q14576 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9665640 | 0.88 | MAOA (0.74) | MAPK8MAOAAMY1APIM1CD38 | |
| SCHEMBL28316302 | 0.86 | MAPT (0.63) | MAPK8MAOAAMY1APIM1CD38 | |
| SCHEMBL25926916 | 0.84 | MAPK8 (1.00) | MAPK8MAOAAMY1APIM1CD38 | |
| SCHEMBL4147950 | 0.83 | ABCG2 (0.81) | MAOAMAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL12640013 | 0.83 | KDM4E (0.79) | MAPK8MAOAAMY1APIM1CD38 | |
| SCHEMBL31126017 | 0.82 | MAOA (0.64) | MAOAMAPTKDM4ECYP3A4MEN1 | |
| Quercetagetin SCHEMBL7647221 | 0.80 | AMY1A (0.89) | MAPK8MAOAAMY1APIM1CD38 | |
| Betuletol SCHEMBL29400938 | 0.77 | TUBB4A (0.86) | MAOAMAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL6563621 | 0.77 | TUBB4A (0.86) | MAOAMAPTKDM4ECYP3A4RECQL | |
| SCHEMBL29059631 | 0.77 | TUBB4A (0.77) | MAPK8MAOAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |