Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18403871 | 0.80 | MEN1 (0.40) | HTR2AMEN1KMT2AADRA2AADRA2B | |
| SCHEMBL15547835 | 0.78 | KDM1A (0.44) | HTR2AMEN1KMT2ASIGMAR1 | |
| SCHEMBL1820390 | 0.75 | MEN1 (0.51) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL22202531 | 0.73 | SIGMAR1 (0.37) | HTR2AMEN1KMT2ASIGMAR1 | |
| SCHEMBL8106287 | 0.72 | HTR2A (0.33) | HTR2AMEN1KMT2ASIGMAR1 | |
| SCHEMBL29498104 | 0.71 | L3MBTL1 (0.46) | HTR2AMEN1KMT2ASIGMAR1 | |
| SCHEMBL1793005 | 0.71 | L3MBTL1 (0.46) | HTR2AMEN1KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL6600350 | 0.70 | L3MBTL1 (0.45) | HTR2AKMT2ASIGMAR1 | |
| SCHEMBL10711927 | 0.70 | SIGMAR1 (0.33) | HTR2ASIGMAR1 | |
| SCHEMBL18091472 | 0.69 | PPIB (0.34) | ADRA2AADRA2BADRA2CADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566850-B1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF IVABRADINE HYDROBROMIDE SALT | RICHTER GEDEON NYRT (HU) | 2018-04-11 | — | — | EP | disclosed |
| EP-2566850-A1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF IVABRADINE SALTS | Richter Gedeon Nyrt. (HU) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138625-A1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF IVABRADINE SALTS | RICHTER GEDEON NYRT. (HU) | 2011-11-10 | — | — | WO | disclosed |