Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19968395 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL12639417 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL12661273 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL9913795 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL2913969 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL14092707 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL12084063 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL14045335 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL29516775 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL21150607 | 0.93 | ACHE (0.32) | MEN1PKMTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4628491-A1 | SYNTHESIS OF INTERMEDIATES FOR THE PREPARATION OF NEUROKININ-3 RECEPTOR ANTAGONISTS | Química Sintética, S.A. (ES) | 2025-10-08 | — | — | EP | claimed |
| EP-4585268-A2 | SOLID FORMS OF ISOQUINOLINONE DERIVATIVES, PROCESS OF MAKING, COMPOSITIONS COMPRISING, AND METHODS OF USING THE SAME | Twelve Therapeutics, Inc. (US) | 2025-07-16 | — | — | EP | claimed |
| EP-4090654-B1 | METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS | LUPIN LTD (IN) | 2025-07-09 | — | — | EP | claimed |
| US-12344592-B2 | Methods, processes and intermediates for preparing chroman compounds | LUPIN LIMITED (IN) | 2025-07-01 | — | — | US | claimed |
| WO-2025122555-A1 | S1P 1 RECEPTOR AGONISTS AND USES THEREOF | VALO HEALTH, INC. (US) | 2025-06-12 | — | — | WO | claimed |
| CN-119819375-A | Method for improving application activity of asymmetric hydrogenation catalyst | 万华化学集团股份有限公司 | 2025-04-15 | — | — | CN | claimed |
| US-20240373736-A1 | Materials and Methods to Improve the Stability of Metal Halide Perovskites | THE UNIVERSITY OF TOLEDO (US) | 2024-11-07 | — | — | US | claimed |
| CN-118119596-A | Preparation method of drug intermediate | 浙江华海药业股份有限公司 | 2024-05-31 | — | — | CN | claimed |
| WO-2024108774-A1 | METAL-CATALYZED DOUBLE HYDROBORATION OF NITROGEN HETEROCYCLICS | GUANGDONG TECHNION-ISRAEL INSTITUTE OF TECHNOLOGY (CN) | 2024-05-30 | — | — | WO | claimed |
| US-11939333-B2 | Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same | INFINITY PHARMACEUTICALS, INC. (US) | 2024-03-26 | — | — | US | claimed |
| CN-116199615-A | Preparation method of ramipril intermediate azabicyclo [3, 0] octane-3 (S) -carboxylic acid | 浙江华海药业股份有限公司 | 2023-06-02 | — | — | CN | claimed |
| CN-116199613-A | Preparation method of perindopril intermediate (2S, 3aS,7 aS) -octahydroindole-2-carboxylic acid | 浙江华海药业股份有限公司 | 2023-06-02 | — | — | CN | claimed |
| EP-4126862-A1 | PROCESS FOR PREPARING A COT INHIBITOR COMPOUND | GILEAD SCIENCES, INC. (US) | 2023-02-08 | — | — | EP | claimed |
| EP-4090654-A1 | METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS | Lupin Limited (IN) | 2022-11-23 | — | — | EP | claimed |
| US-20220135576-A1 | SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME | TWELVE THERAPEUTICS, INC. | 2022-05-05 | — | — | US | claimed |
| US-20220048917-A1 | HIGHLY EFFICIENT PROCESS FOR THE PREPARATION OF SITAGLIPTIN VIA RHODIUM CATALYZED ASYMMETRIC HYDROGENATION | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-02-17 | — | — | US | claimed |
| CN-113968872-A | Preparation method of phenyl substituted ACC inhibitor | 南京圣和药业股份有限公司 | 2022-01-25 | — | — | CN | claimed |
| US-20210104686-A1 | Materials and Methods to Improve the Stability of Metal Halide Perovskites | THE UNIVERSITY OF TOLEDO (US) | 2021-04-08 | — | — | US | claimed |
| WO-2020121321-A1 | HIGHLY EFFICIENT PROCESS FOR THE PREPARATION OF SITAGLIPTIN VIA RHODIUM CATALYZED ASYMMETRIC HYDROGENATION | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-06-18 | — | — | WO | claimed |
| EP-1622918-B1 | PHOSPHOLANE SALTS AND THEIR USE IN ENANTIOSELECTIVE HYDROGENATION | SOLVIAS AG (CH) | 2010-03-24 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048917-A1 | HIGHLY EFFICIENT PROCESS FOR THE PREPARATION OF SITAGLIPTIN VIA RHODIUM CATALYZED ASYMMETRIC HYDROGENATION | DPP4, DPP7, DPP9 | MEN1 556/4885PKM 1269/4885TSHR 835/4885 |
| US-20220135576-A1 | SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME | PIK3CA, PIK3C2A, PIK3CD | MEN1 3126/4885PKM 464/4885TSHR 4794/4885 |
| US-11939333-B2 | Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same | PIK3CA, PIK3C2A, PIK3CD | MEN1 3126/4885PKM 464/4885TSHR 4794/4885 |
| US-20210104686-A1 | Materials and Methods to Improve the Stability of Metal Halide Perovskites | SOD1, BMI1, VCL | MEN1 250/4885PKM 2844/4885TSHR 4027/4885 |
| US-20240373736-A1 | Materials and Methods to Improve the Stability of Metal Halide Perovskites | SOD1, BMI1, VCL | MEN1 250/4885PKM 2844/4885TSHR 4027/4885 |
| US-12344592-B2 | Methods, processes and intermediates for preparing chroman compounds | CASR, CALCR, RYR1 | MEN1 1359/4885PKM 2249/4885TSHR 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.