Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19968395 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL12639417 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL12661273 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL2913969 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL14092707 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL12084063 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL14045335 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL29516775 | 1.00 | MEN1 (0.33) | MEN1PKMTSHRKMT2A | |
| SCHEMBL21150607 | 0.93 | ACHE (0.32) | MEN1PKMTSHRKMT2A | |
| SCHEMBL21150260 | 0.93 | MEN1 (0.31) | MEN1PKMTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220176363-A1 | PROCESS FOR OLIGOMERIZATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-06-09 | — | — | US | disclosed |
| US-20220048917-A1 | HIGHLY EFFICIENT PROCESS FOR THE PREPARATION OF SITAGLIPTIN VIA RHODIUM CATALYZED ASYMMETRIC HYDROGENATION | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-02-17 | — | — | US | disclosed |
| CN-113896607-A | Olefin oligomerization process using catalyst comprising chromium complex with phosphacycle-containing ligand | 陶氏环球技术有限责任公司 | 2022-01-07 | — | — | CN | disclosed |
| CN-107592863-B | Chromium complexes with ligands containing phosphacycles and olefin oligomerization catalysts therefrom | 陶氏环球技术有限责任公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-107567355-B | Phosphacycle-containing ligands for chromium complexes and olefin oligomerization catalysts therefrom | 陶氏环球技术有限责任公司 | 2021-07-23 | — | — | CN | disclosed |
| US-20210129125-A1 | PROCESS FOR OLIGOMERIZATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-05-06 | — | — | US | disclosed |
| US-10981156-B2 | Chromium complex and catalyst therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-04-20 | — | — | US | disclosed |
| US-10919031-B2 | Process for oligomerization | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-02-16 | — | — | US | disclosed |
| US-20200338542-A1 | PROCESS FOR OLIGOMERIZATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-10-29 | — | — | US | disclosed |
| WO-2020194337-A2 | A PROCESS FOR THE ASYMMETRIC SYNTHESIS OF SITAGLIPTIN INTERMEDIATE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2020-10-01 | — | — | WO | disclosed |
| EP-1849792-B1 | Biphosphine ruthenium complexes with chiral diamine ligands as catalysts | JOHNSON MATTHEY PLC (GB) | 2008-12-10 | — | — | EP | disclosed |
| WO-2008119161-A1 | METHODS OF PREPARING SECONDARY CARBINAMINE COMPOUNDS WITH BORONIC ACIDS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119162-A1 | METHODS OF PREPARING PRIMARY, SECONDARY AND TERTIARY CARBINAMINE COMPOUNDS IN THE PRESENCE OF AMMONIA | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2008-10-09 | — | — | WO | disclosed |
| US-20080154047-A1 | Process For the Preparation of Enantiomerically Pure1-Substitued-3-Aminoalcohols | LONZA AG (CH) | 2008-06-26 | — | — | US | disclosed |
| US-20080039639-A1 | Chromane and chromene derivatives and uses thereof | WYETH (US) | 2008-02-14 | — | — | US | disclosed |
| US-20080039639-A1 | Chromane and chromene derivatives and uses thereof | WYETH (US) | 2008-02-14 | — | — | US | disclosed |
| EP-1849792-A1 | Biphosphine ruthenium complexes with chiral diamine ligands as catalysts | Johnson Matthey PLC (GB) | 2007-10-31 | — | — | EP | disclosed |
| US-7235510-B2 | Catalysts | JOHNSON MATTHEY PLC (GB) | 2007-06-26 | — | — | US | disclosed |
| US-20070088022-A1 | Tetrahydroquinolines, synthesis thereof, and intermediates thereto | WYETH (US) | 2007-04-19 | — | — | US | disclosed |
| US-20070066850-A1 | Catalysts | JOHNSON MATTHEY PLC (GB) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088022-A1 | Tetrahydroquinolines, synthesis thereof, and intermediates thereto | HTR2C, HTR3B, HTR2A | MEN1 1319/4885PKM 3335/4885TSHR 642/4885 |
| US-20210129125-A1 | PROCESS FOR OLIGOMERIZATION | OXER1, NOD1, LIG1 | MEN1 1539/4885PKM 2978/4885TSHR 4279/4885 |
| US-20200338542-A1 | PROCESS FOR OLIGOMERIZATION | OXER1, NOD1, LIG1 | MEN1 1539/4885PKM 2978/4885TSHR 4279/4885 |
| US-20070066850-A1 | Catalysts | HRH3, PRMT1, HRH4 | MEN1 694/4885PKM 1636/4885TSHR 957/4885 |
| US-20220048917-A1 | HIGHLY EFFICIENT PROCESS FOR THE PREPARATION OF SITAGLIPTIN VIA RHODIUM CATALYZED ASYMMETRIC HYDROGENATION | DPP4, DPP7, DPP9 | MEN1 556/4885PKM 1269/4885TSHR 835/4885 |
| US-10919031-B2 | Process for oligomerization | OXER1, NOD1, LIG1 | MEN1 1539/4885PKM 2978/4885TSHR 4279/4885 |
| US-20080039639-A1 | Chromane and chromene derivatives and uses thereof | HTR1A, CHRM1, HTR2C | MEN1 1074/4885PKM 2411/4885TSHR 68/4885 |
| US-10981156-B2 | Chromium complex and catalyst therefrom | OXER1, LIG1, PICALM | MEN1 2246/4885PKM 707/4885TSHR 4123/4885 |
| US-20080154047-A1 | Process For the Preparation of Enantiomerically Pure1-Substitued-3-Aminoalcohols | ADH1A, ADH1C, ALDH7A1 | MEN1 1729/4885PKM 104/4885TSHR 3042/4885 |
| US-20220176363-A1 | PROCESS FOR OLIGOMERIZATION | OXER1, NOD1, LIG1 | MEN1 1539/4885PKM 2978/4885TSHR 4279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.