Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21207960 | 0.94 | ADRB2 (0.47) | SMN1; SMN2LMNAHTTKDM4EALDH1A1 | |
| SCHEMBL3925230 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTTSHRKDM4E | |
| SCHEMBL16437099 | 0.89 | TSHR (0.58) | SMN1; SMN2LMNAHTTTSHRKDM4E | |
| SCHEMBL607698 | 0.89 | TSHR (0.58) | SMN1; SMN2LMNAHTTTSHRKDM4E | |
| SCHEMBL3552086 | 0.89 | TSHR (0.58) | SMN1; SMN2LMNAHTTTSHRKDM4E | |
| SCHEMBL606328 | 0.89 | TSHR (0.58) | SMN1; SMN2LMNAHTTTSHRKDM4E | |
| SCHEMBL12865302 | 0.89 | TSHR (0.58) | SMN1; SMN2LMNAHTTTSHRKDM4E | |
| SCHEMBL599527 | 0.89 | TSHR (0.58) | SMN1; SMN2LMNAHTTTSHRKDM4E | |
| SCHEMBL24748 | 0.89 | TSHR (0.58) | SMN1; SMN2LMNAHTTTSHRKDM4E | |
| SCHEMBL607716 | 0.89 | TSHR (0.58) | SMN1; SMN2LMNAHTTTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137516-A1 | FLAVONOID DIMERS AND THEIR USE | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY (CA) | 2011-11-10 | — | — | WO | disclosed |